Over the past decade, innovations in both sequencing technology and computational biology have led to a growing interest in profiling human microbiota for therapeutic and diagnostic applications.
Recent research has highlighted how human microbiome is increasingly demonstrated as a central component of personalized medicine. Beyond well known the inter-individual variability, microbiome could represent a modifiable feature to be addressed in personalized treatment.
While most of the research remain in their early stages, specific microbial signature has already been associated with cancer promotion, inflammatory bowel disease, neurodegenerative, skin or gynecological conditions. Emergence of applications in the diagnostic area is anticipated to bring high value as innovative biomarkers for many critical conditions.
In this Ask the Expert session, we answered questions concerning topics such as:
- Under what regulatory environment would microbiome-based diagnostics fall?
- What are the best approaches & practices to ensure performance of testing in clinical labs regarding the new genomic technologies and microbial sequence data analysis?
- What important methodological considerations must be anticipated for microbiome diagnostic?