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Real World Study (RWS)
Real World Study (RWS)
Studies investigating health interventions whose design does not follow the design of a highly-controlled RCT and aims to reflect health intervention effectiveness in routine clinical practice. Real world studies do not typically include randomisation of trial subjects, but there are exceptions (e.g. pragmatic clinical trials). RWS, by definition, generate RWD, which can subsequently be analysed and/or synthesised to produce RWE.